Caffeine is a bitter, white crystalline xanthine alkaloid that is a psychoactive stimulant. Caffeine was isolated from coffee in 1820 by a German chemist, Friedlieb Ferdinand Runge, and in 1821 by French chemists working independently; namely, by Robiquet and by Pelletier and Caventou. It was Pelletier, noting that the drug had been isolated from coffee (French: café), who coined the word "cafeine", which became the English word "caffeine".In humans, caffeine acts as a central nervous system (CNS) stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is the world's most widely consumed psychoactive substance, but, unlike many other psychoactive substances, is legal and unregulated in nearly all jurisdictions.
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